BARRY'S BOOKS


New book in Dutch

Eet vet word slank

Eet vet word slank gepubliceerd januari 2013

In dit boek lees je o.a.: * heel veel informatie ter bevordering van je gezondheid; * hoe je door de juiste vetten te eten en te drinken kan afvallen; * hoe de overheid en de voedingsindustrie ons, uit financieel belang, verkeerd voorlichten; * dat je van bewerkte vetten ziek kan worden.


Trick and Treat:
How 'healthy eating' is making us ill
Trick and Treat cover

"A great book that shatters so many of the nutritional fantasies and fads of the last twenty years. Read it and prolong your life."
Clarissa Dickson Wright


Natural Health & Weight Loss cover

"NH&WL may be the best non-technical book on diet ever written"
Joel Kauffman, PhD, Professor Emeritus, University of the Sciences, Philadelphia, PA




 
 
   
 
   
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Effect of various genotoxins and reproductive toxins in human lymphocytes and sperm in the Comet assay


Anderson D, Dobrzyska MM, Basaran N

Teratog Carcinog Mutagen 1997 17:1 29-43

Abstract

There have been conflicting reports as to whether the mean sperm count in some men has diminished over the last 50 years. The downward trend has been suggested to coincide with an increase in exposure to estrogen-like compounds.

These estrogenic substances are ubiquitous in the environment.

We have examined the effect of such substances (diethylstilbestrol, beta-estradiol, daidzein, genestein, and nonylphenyl) in the single cell gel electrophoresis assay (Comet assay) in human sperm and compared responses with those from human peripheral lymphocytes in the same donor and in peripheral lymphocytes from a female donor.

In addition, effects from the estrogens have been compared to those from known reprotoxins and genotoxins. These include lead sulfate, nitrate and acetate, dibromochloropropane, ethylene glycol monoethyl ether, 1,2-epoxybutene, and 1,2,3,4-diepoxybutane.

All compounds produced positive responses, but ethylene glycol monoethyl ether only produced positive responses in sperm cells in the male and not in peripheral lymphocytes, and similarly the phytoestrogens (genistein, daidzein) were less responsive in the peripheral lymphocytes in the male than in the sperm.

This may be due to greater sensitivity of sperm cells because of their lack of repair.

However, since damage was generally seen over a similar dose range, a one-to-one ratio of somatic and germ cell damage was observed and has implications for man for risk assessment purposes

 




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